In this episode, I am joined by Nicholas Silvestri, Professor of Neurology at the University at Buffalo Jacobs School of Medicine and Biomedical Sciences, where he is also Associate Dean for Student and Academic Affairs. He is board-certified in neurology, neuromuscular medicine, and electrodiagnostic medicine.
Our conversation covers the full spectrum of myasthenia gravis – from its pathology and pathogenesis to its clinical features, investigations and treatments. He explains such tricky areas of myasthenia gravis, such as why the antibody levels do not correlate with clinical severity of the disease, and why the disease frequently starts in the ocular muscles.
We also explored such themes as why anti MUSK myasthenia gravis favours Black people and those living around the equator, and why steroid treatment may worsen myasthenic symptoms.
Nicholas Silvestri also discussed the newer and more effective treatments of refractory myasthenia gravis, and how he manages the different facets of the disease.
Over the past several years, Nicholas Silvestri’s research interests have included myasthenia gravis and inflammatory neuropathies, and he has authored over 60 peer-reviewed articles, book chapters, and textbooks.
Watch it on YouTube:https://youtu.be/U7QQZ5o19C8
Listen to it on Spotify:https://open.spotify.com/episode/6TWL16dR5IXvAwpdsK4zaZ
Listen to it on RSS feedhttps://rss.com/podcasts/theneurologylounge/1761210/
Listen to it on Apple podcastshttps://tinyurl.com/bs6sxxne
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The Neurology Lounge 
