At first, it seemed like a single drop, but it is quickly turning into a trickle. The first inkling was a study of >1,700 people with motor neurone disease (MND) which was published in the journal Neurology titled Depression in amyotrophic lateral sclerosis. The authors found that depression is a very frequent diagnosis shortly before people are diagnosed with… Read More The emerging links between depression and MND
Of all the disorders neurologists have to deal with, few have as many subtypes as spinocerebellar ataxia (SCA). Most neurologist are familiar with the more common SCAs-types 1,2,3,6, and 7. When pushed, SCA17 will pop into the mind…just because of its similarity to Huntington’s disease (HD). At the last count, there are 43 different forms… Read More The 43 spinocerebellar ataxias: the complete checklists
I have dabbled into gluten neurology before with my post gluten neurology-persisting and growing? Prophetic it seems, as I am here forced to revisit the topic because I came across a few recent interesting reports on the neurology of gluten. Gluten psychosis Take this case report from Nutrients titled gluten psychosis: confirmation of a new clinical… Read More More activity on the fringes of gluten neurology
Epilepsy is a big problem for Neurology. It is a common, and often life-long, disease. Epilepsy is like the mythical hydra in its diverse manifestations, and in its duplicitous evasion of treatment. The pillars of epilepsy treatment are the anti-epileptic drugs (AEDs). It is however a very tricky business to wield these very powerful tools.… Read More The 29 proven anti-epilepsy drugs…and their practical checklists
This is a follow up to my previous blog post titled The emerging research boosting Parkinson’s disease treatment. That post reviewed breakthroughs in the treatment of Parkinson’s disease (PD). But what are the advances in preventing the dreaded disease? What is the state of neuroprotection in PD? What are the hopes for attaining this elusive holy grail of neurology, the… Read More What are the drugs promising neuroprotection in PD?
Many neurological disorders and syndromes have very long and windy names. To bypass these tongue-twisting appellations, neurologists have become adept at coming up with great and catchy acronyms. Many neurological acronyms are very short, for example multiple sclerosis (MS), and Parkinosn’s disease (PD). Some are slightly longer, with three or four letters, for example frontotemporal… Read More 30 neurological disorders with long ACRONYMS…and their checklists
Mendelian randomization shows a causal effect of low vitamin D on multiple sclerosis risk Rhead B, Bäärnhielm M, Gianfrancesco M, et al. Neurol Genet 2016; 2:e97. Abstract OBJECTIVE: We sought to estimate the causal effect of low serum 25(OH)D on multiple sclerosis (MS) susceptibility that is not confounded by environmental or lifestyle factors or subject […]… Read More Is low vitamin D a cause of multiple sclerosis?