Parkinson’s disease (PD) is probably the most iconic neurological disorder. It has diverse manifestations, typical of many neurological diseases. PD is a result of brain dopamine deficiency, and its clinical picture is dominated by motor symptoms- tremor, rigidity and bradykinesia (slowing of movements). It however also manifests with a variety of non-motor symptoms which rival the motor symptoms in their… Read More The emerging research boosting Parkinson’s disease treatment
This is a follow up to my last blog post titled What has the Exeter neurology course accomplished in the last decade? There I discussed the achievements of the West of England Seminars in Advanced Neurology (WESAN). In this post, the focus is on the history of WESAN, and who better to tell the story than Christopher Gardner-Thorpe, who spent the… Read More A short history of WESAN
The West of England Seminars in Advanced Neurology (WESAN) is a neurology course which holds annually in Exeter, the historic English city in the scenic county of Devon. It is a highly-regarded, even if a little bit unassuming, neurology meeting. Over the last decade I have attended several WESAN conferences, always going back to base buzzing with neurological enthusiasm, and brimming… Read More What has the Exeter neurology course accomplished in the last decade?
In the process of writing a blog post on the research findings altering neurological practice, my sight fell on the drug, Masitinib. I was completely unaware of this tyrosine kinase inhibitor, one of the promising drugs in the fight against multiple sclerosis (MS). We are likely to hear a lot more about Masitinib in MS in the coming months.… Read More Masitinib, a breakthrough drug shattering neurology boundaries
In the excellent book, The Innovators Prescription, the authors predict that precision medicine will replace intuitive medicine, and diseases will be defined by their underlying metabolic mechanisms, and not by the organs they affect, or the symptoms they produce. Clayton Christensen and colleagues argue that this precise definition of diseases will lead to more effective treatments. But they also show that precision… Read More Alzheimers disease and its promising links with diabetes
Dystonia is probably the most nebulous of neurological terms. Neurologists use the term for a vast array of neurological diseases. Dystonia also crops up as part of many complex neurological syndromes. Worse still, neurologists also use the name dystonia as a symptom. All quite confusing and perplexing for the lay observer. No wonder dystonia defies simple definitions. Take the National Institute of… Read More Why does dystonia fascinate and challenge neurology?
Seahorses are beautiful creatures. The biologists convince us that seahorses are fish, even if they don’t look anything like fish. They also tell us, intriguingly, that seahorses are monogamous and the males do the childbearing. But why is a neurologist talking about seahorses. It’s all in the name. The Latin name for seahorse is hippocampus , derived… Read More Depression and the shrinking seahorses in the brain