Gd contrast administration is dispensable in patients with MS without new T2 lesions on follow-up MRI Karimian-Jazi K, Wildemann B, Diem R, et al. Neurol Neuroimmunol Neuroinflamm 2018; 5:e480. Abstract OBJECTIVE: To assess the diagnostic value of gadolinium (Gd) contrast administration in MRI follow-up examinations of patients with MS if the T2 lesion load […]
via Is gadolinium necessary in multiple sclerosis follow up brain scans? — Neurochecklists Updates
Multicentre, cross-cultural, population-based, case-control study of physical activity as risk factor for amyotrophic lateral sclerosis. Visser AE, Rooney JPK, D’Ovidio F, et al; Euro-MOTOR consortium. JNNP 2018; 89:797-803. Abstract OBJECTIVE: To investigate the association between physical activity (PA) and amyotrophic lateral sclerosis (ALS) in population-based case-control studies in three European countries using a validated and […]
via Is physical activity a risk factor for MND? — Neurochecklists Updates
The Edinburgh CT and genetic diagnostic criteria for lobar intracerebral haemorrhage associated with cerebral amyloid angiopathy: model development and diagnostic test accuracy study. Rodrigues MA, Samarasekera N, Lerpiniere C, et al. Lancet Neurol 2018; 17:232-240. Abstract BACKGROUND: Identification of lobar spontaneous intracerebral haemorrhage associated with cerebral amyloid angiopathy (CAA) is important because it is associated […]
via What factors predict bleeding from cerebral amyloid angiopathy? — Neurochecklists Updates
Measles may be a risk factor for malignant brain tumors. Lehrer S, Green S, Rendo A, Rosenzweig KE. Brain Tumor Res Treat 2015; 3:65-67. Abstract BACKGROUND: A possible risk factor for brain tumor might be measles, since late neurologic sequelae are part of measles pathology. Subacute sclerosing panencephalitis, a devastating neurologic illness, is prone to […]
via Is measles infection a risk factor for brain tumours? — Neurochecklists Updates
Cervical spinal cord atrophy: an early marker of progressive MS onset. Zeydan B, Gu X, Atkinson EJ, et al. Neurol Neuroimmunol Neuroinflamm 2018; 5:e435. Abstract OBJECTIVE: To assess whether cervical spinal cord atrophy heralds the onset of progressive MS. METHODS: We studied 34 individuals with radiologically isolated syndrome (RIS) and 31 patients with relapsing-remitting MS (RRMS) agematched to 25 patients within a year of onset of secondary […]
via What is the radiological hallmark of secondary progressive MS? — Neurochecklists Updates
Identification of shared molecular signatures indicate the susceptibility of endometriosis to multiple sclerosis. Katiyar A, Sharma S, Singh TP, Kaur P. Front Genet 2018; 9:42. Abstract BACKGROUND: Women with endometriosis (EMS) appear to be at a higher risk of developing other autoimmune diseases predominantly multiple sclerosis (MS). Though EMS and MS are evidently diverse in […]
via How does endometriosis increase the risk of multiple sclerosis? — Neurochecklists Updates
Aminophylline for treatment of postdural puncture headache: a randomized clinical trial. Wu C, Guan D, Ren M, et al. Neurology 2018; 90:e1523-e1529. Abstract OBJECTIVE: To investigate the efficacy and safety of IV aminophylline for patients with postdural puncture headache (PDPH). METHODS: We randomly assigned patients to groups receiving either 250 mg IV aminophylline or a placebo within 3 hours of symptom […]
via How effective is aminophylline for post dural puncture headache? — Neurochecklists Updates
