Is measles infection a risk factor for brain tumours?

Measles may be a risk factor for malignant brain tumors. Lehrer S, Green S, Rendo A, Rosenzweig KE. Brain Tumor Res Treat 2015; 3:65-67. Abstract BACKGROUND: A possible risk factor for brain tumor might be measles, since late neurologic sequelae are part of measles pathology. Subacute sclerosing panencephalitis, a devastating neurologic illness, is prone to […]

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What is the radiological hallmark of secondary progressive MS?

Cervical spinal cord atrophy: an early marker of progressive MS onset. Zeydan B, Gu X, Atkinson EJ, et al. Neurol Neuroimmunol Neuroinflamm 2018; 5:e435. Abstract OBJECTIVE: To assess whether cervical spinal cord atrophy heralds the onset of progressive MS. METHODS: We studied 34 individuals with radiologically isolated syndrome (RIS) and 31 patients with relapsing-remitting MS (RRMS) agematched to 25 patients within a year of onset of secondary […]

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Are artists immune from Parkinson’s disease?

Professional occupation and the risk of Parkinson’s disease Darweesh SKL, Ikram MK, Faber MJ, et al Eur J Neurol 2018 (Epub ahead of print) Abstract BACKGROUND: Creativity in Parkinson’s disease (PD) is strongly related to dopaminergic activity and medication. We hypothesized that patients with PD, including those who are in the pre-diagnostic phase of PD, are prone […]

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How does endometriosis increase the risk of multiple sclerosis?

Identification of shared molecular signatures indicate the susceptibility of endometriosis to multiple sclerosis. Katiyar A, Sharma S, Singh TP, Kaur P. Front Genet 2018; 9:42. Abstract BACKGROUND: Women with endometriosis (EMS) appear to be at a higher risk of developing other autoimmune diseases predominantly multiple sclerosis (MS). Though EMS and MS are evidently diverse in […]

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How effective is aminophylline for post dural puncture headache?

Aminophylline for treatment of postdural puncture headache: a randomized clinical trial. Wu C, Guan D, Ren M, et al. Neurology 2018; 90:e1523-e1529. Abstract OBJECTIVE: To investigate the efficacy and safety of IV aminophylline for patients with postdural puncture headache (PDPH). METHODS: We randomly assigned patients to groups receiving either 250 mg IV aminophylline or a placebo within 3 hours of symptom […]

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What are the important causes of small fiber neuropathy?

Associated conditions in small fiber neuropathy-a large cohort study and review of the literature. de Greef BTA, Hoeijmakers JGJ, Gorissen-Brouwers CML, Geerts M, Faber CG, Merkies ISJ. Eur J Neurol 2018; 25:348-355. Abstract BACKGROUND AND PURPOSE: Small fiber neuropathy (SFN) is a common disorder leading to neuropathic pain and autonomic symptoms. The objective of this […]

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How does the 10/20 rule differentiate syncope from seizures?

Differentiating motor phenomena in tilt-induced syncope and convulsive seizures. Shmuely S, Bauer PR, van Zwet EW, van Dijk JG, Thijs RD. Neurology 2018; 90:e1339-e1346. Abstract OBJECTIVE: We assessed motor phenomena in syncope and convulsive seizures to aid differential diagnosis and understand the pathophysiologic correlates. METHODS: We studied video-EEG recordings of tilt-induced syncope and convulsive seizures […]

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