Is thrombolysis beneficial when time of stroke onset is unknown?

Efficacy and safety of thrombolytic therapy for stroke with unknown time of onset: a meta-analysis of observational studies. Zhu RL, Xu J, Xie CJ, Hu Y, Wang K. J Stroke Cerebrovasc Dis 2020 (Epub ahead of print). Abstract BACKGROUND: Recombinant tissue plasminogen activator (rt-PA) is one of the most effective therapies available for patients with […]

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Does breastfeeding influence the risk of postpartum MS relapses?

Association between breastfeeding and postpartum multiple sclerosis relapses: a systematic review and meta-analysis. Krysko KM, Rutatangwa A, Graves J, Lazar A, Waubant E. JAMA Neurol 2019 (Epub ahead of print). Abstract BACKGROUND: Multiple sclerosis (MS) relapses may be increased in the postpartum period, and whether breastfeeding is associated with reduction in the risk of postpartum […]

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Patient H.M.

Patient H. M. Author: Luke Dittrich Synopsis This is a unique and even controversial biography of a person the author described as ‘the most studied individual in the history of neuroscience’ (page 8). Patient H.M., now known to be Henry Molaison, perhaps more than any other patient, helped to delineate how the brain functions. What […]

via Patient H.M. — The Doctors Bookshelf

10 more catchy titles from the recent neurology literature

How effective is stem cell transplantation for NMO?

Autologous nonmyeloablative hematopoietic stem cell transplantation for neuromyelitis optica. Burt RK, Balabanov R, Han X, et al. Neurology 2019; 93:e1732-e1741. Abstract OBJECTIVE: To determine if autologous nonmyeloablative hematopoietic stem cell transplantation (HSCT) could be a salvage therapy for neuromyelitis optica spectrum disorder (NMOSD). METHODS: Thirteen patients were enrolled in a prospective open-label cohort study (11 […]

via How effective is stem cell transplantation for NMO? — Neurochecklists Blog

Remembering

Remembering Author: Donald G McKay Synopsis This book is about Patient HM, probably the most important patient in the history of neuroscience because of what his brain revealed about how memory works. Known since his death by his real name, Henry Molaison, he developed profound amnesia following brain surgery to treat uncontrolled epilepsy, and the […]

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Permanent Present Tense

Permanent Present Tense Author: Suzanne Corkin Synopsis Henry Molaison, known throughout his life as Patient H.M, is the fateful neuroscience patient whose misfortune completely redefined our understanding of the inner workings of the brain. This book explores the amnesia Henry developed following unprecedented brain surgery for severe epilepsy, a unique disability that made him ‘the gold […]

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