Gyrification abnormalities in presymptomatic c9orf72 expansion carriers Caverzasi E, Battistella G, Chu SA, et al. JNNP 2019; 90:1005-1010. Abstract OBJECTIVE: To investigate in-vivo cortical gyrification patterns measured by the local gyrification index (lGI) in presymptomatic c9orf72 expansion carriers compared with healthy controls, and investigate relationships between lGI and cortical thickness, an established morphometric measure of neurodegeneration. METHODS: […]

via Do pre-symptomatic c9orf72 carriers have a brain MRI signature? — Neurochecklists Blog

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