How does endometriosis increase the risk of multiple sclerosis?

Identification of shared molecular signatures indicate the susceptibility of endometriosis to multiple sclerosis. Katiyar A, Sharma S, Singh TP, Kaur P. Front Genet 2018; 9:42. Abstract BACKGROUND: Women with endometriosis (EMS) appear to be at a higher risk of developing other autoimmune diseases predominantly multiple sclerosis (MS). Though EMS and MS are evidently diverse in […]

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How effective is aminophylline for post dural puncture headache?

Aminophylline for treatment of postdural puncture headache: a randomized clinical trial. Wu C, Guan D, Ren M, et al. Neurology 2018; 90:e1523-e1529. Abstract OBJECTIVE: To investigate the efficacy and safety of IV aminophylline for patients with postdural puncture headache (PDPH). METHODS: We randomly assigned patients to groups receiving either 250 mg IV aminophylline or a placebo within 3 hours of symptom […]

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What are the important causes of small fiber neuropathy?

Associated conditions in small fiber neuropathy-a large cohort study and review of the literature. de Greef BTA, Hoeijmakers JGJ, Gorissen-Brouwers CML, Geerts M, Faber CG, Merkies ISJ. Eur J Neurol 2018; 25:348-355. Abstract BACKGROUND AND PURPOSE: Small fiber neuropathy (SFN) is a common disorder leading to neuropathic pain and autonomic symptoms. The objective of this […]

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How does the 10/20 rule differentiate syncope from seizures?

Differentiating motor phenomena in tilt-induced syncope and convulsive seizures. Shmuely S, Bauer PR, van Zwet EW, van Dijk JG, Thijs RD. Neurology 2018; 90:e1339-e1346. Abstract OBJECTIVE: We assessed motor phenomena in syncope and convulsive seizures to aid differential diagnosis and understand the pathophysiologic correlates. METHODS: We studied video-EEG recordings of tilt-induced syncope and convulsive seizures […]

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Is normal pressure hydrocephalus a risk factor for Alzheimer’s disease?

Concurrent Alzheimer’s pathology in patients with clinical normal pressure hydrocephalus Pomeraniec IJ, Taylor DG, Bond AE, Lopes MB J Neurosurg Sci 2018 (Epub ahead of print) Abstract BACKGROUND: Patients with normal pressure hydrocephalus (NPH) and Alzheimer’s dementia (AD) can often present with similar symptoms. NPH remains a clinical diagnosis and there are reported shared underlying […]

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Does influenza vaccination reduce the risk of stroke?

The association of adult vaccination with the risk of cerebrovascular ischemia: a systematic review and meta-analysis Tsivgoulis G, Katsanos AH, Zand R, et al. J Neurol Sci 2018; 386:12-18. Abstract Background: There is mounting evidence supporting infection as an independent risk factor for ischemic stroke (IS), while preliminary data indicate that vaccination may prevent IS. […]

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Does diabetes reduce the risk of migraine?

Diabetes is associated with decreased migraine risk: a nationwide cohort study Antonazzo IC, Riise T, Cortese M, et al. Cephalalgia 2017 (Epub ahead of print). Abstract Background: Results from studies on diabetes and migraine risk are conflicting, which may be due to methodological limitations. Prospective studies with long follow-up could increase our understanding of the […]

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