The 20 most popular neurochecklists blog posts of 2018

2018 started a 100 posts ago. A busy year for the blog. How time flies! A year of asking questions… And seeking answers… One blog post at a time. So which of our blog posts… Old or new… Attracted the most attention in 2018? Here are the 20 most popular neurochecklists blog posts […]

via The 20 most popular neurochecklists blog posts of 2018 — Neurochecklists Updates

Does valproate affect male reproductive function?

Effects of valproate on reproductive endocrine function in male patients with epilepsy: a systematic review and meta-analysis. Zhao S, Wang X, Wang Y, et al. Epilepsy Behav 2018; 85:120-128. Abstract BACKGROUND: Valproate (VPA) is a broad spectrum antiepileptic drug (AED) that is generally used as a first line agent for most idiopathic and symptomatic generalized epilepsies. Many […]

via Does valproate affect male reproductive function? — Neurochecklists Updates

Is gadolinium necessary in multiple sclerosis follow up brain scans?

Gd contrast administration is dispensable in patients with MS without new T2 lesions on follow-up MRI Karimian-Jazi K, Wildemann B, Diem R, et al. Neurol Neuroimmunol Neuroinflamm 2018; 5:e480. Abstract OBJECTIVE: To assess the diagnostic value of gadolinium (Gd) contrast administration in MRI follow-up examinations of patients with MS if the T2 lesion load […]

via Is gadolinium necessary in multiple sclerosis follow up brain scans? — Neurochecklists Updates

Is physical activity a risk factor for MND?

Multicentre, cross-cultural, population-based, case-control study of physical activity as risk factor for amyotrophic lateral sclerosis. Visser AE, Rooney JPK, D’Ovidio F, et al; Euro-MOTOR consortium. JNNP 2018; 89:797-803. Abstract OBJECTIVE: To investigate the association between physical activity (PA) and amyotrophic lateral sclerosis (ALS) in population-based case-control studies in three European countries using a validated and […]

via Is physical activity a risk factor for MND? — Neurochecklists Updates

What factors predict bleeding from cerebral amyloid angiopathy?

The Edinburgh CT and genetic diagnostic criteria for lobar intracerebral haemorrhage associated with cerebral amyloid angiopathy: model development and diagnostic test accuracy study. Rodrigues MA, Samarasekera N, Lerpiniere C, et al. Lancet Neurol 2018; 17:232-240. Abstract BACKGROUND: Identification of lobar spontaneous intracerebral haemorrhage associated with cerebral amyloid angiopathy (CAA) is important because it is associated […]

via What factors predict bleeding from cerebral amyloid angiopathy? — Neurochecklists Updates

Is measles infection a risk factor for brain tumours?

Measles may be a risk factor for malignant brain tumors. Lehrer S, Green S, Rendo A, Rosenzweig KE. Brain Tumor Res Treat 2015; 3:65-67. Abstract BACKGROUND: A possible risk factor for brain tumor might be measles, since late neurologic sequelae are part of measles pathology. Subacute sclerosing panencephalitis, a devastating neurologic illness, is prone to […]

via Is measles infection a risk factor for brain tumours? — Neurochecklists Updates

What is the radiological hallmark of secondary progressive MS?

Cervical spinal cord atrophy: an early marker of progressive MS onset. Zeydan B, Gu X, Atkinson EJ, et al. Neurol Neuroimmunol Neuroinflamm 2018; 5:e435. Abstract OBJECTIVE: To assess whether cervical spinal cord atrophy heralds the onset of progressive MS. METHODS: We studied 34 individuals with radiologically isolated syndrome (RIS) and 31 patients with relapsing-remitting MS (RRMS) agematched to 25 patients within a year of onset of secondary […]

via What is the radiological hallmark of secondary progressive MS? — Neurochecklists Updates