Old drugs, new roles?

Three recent articles caught my interest because they point to potential new roles for old drugs.

The first paper in the Lancet Neurology  suggests a role for Riluzole in hereditary cerebellar ataxia. With 50% of the treatment arm improving against 11% of the placebo arm, I hope this is not false hope for patients with Friedreich’s ataxia (FA) and spinocerebellar ataxia (SCA).

By Kamil9243 - Own work, CC BY 3.0, Link
By Kamil9243Own work, CC BY 3.0, Link

The second paper in Neurology reports that Statins reduce the risk of post-stroke seizures. You say hmmm, they say more studies needed.

By Solidach - With software of which I am the product manager, CC BY-SA 3.0, Link
By Solidach – With software of which I am the product manager, CC BY-SA 3.0, Link

The third paper in JNNP points to the benefit (or not) of Dantrolene for subarachnoid haemorrhage vasospasm. Feasible, tolearable and safe… but study not powered to detect efficacy!

By Jynto (talk) - Own workThis chemical image was created with Discovery Studio Visualizer., CC0, Link
By Jynto (talk) – Own workThis chemical image was created with Discovery Studio Visualizer., CC0, Link

Keep up with the expanding role of drugs in neurology with my recent blog posts:

 

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