It was the final day of the American Association of Neurology (ANA) conference yesterday and prion diseases took center stage. John Collinge, the only prominent British presence at the conference, set the ball rolling with insights into the potential treatment of CJD with anti-PrP monoclonal antibodies. But it wasn’t the day for traditional prion… Read More Final day of ANA 2015- Prions center stage
Its day 3 about to start at the American Neurological Association (ANA) annual conference. As a follow up tp my previous posts, this is a quick take on 6 new buzzwords for me from day 2. These are at the cutting edge of neurology Metagenomic deep sequencing. This promises to solve the pervasive problem of… Read More 6 buzzwords from day 2 ANA Chicago 2015
Before day 2 commences, a quick word on a wonderful symposium on Multiple Sclerosis (MS). MS epidemiologists and researchers dissected the topic Causes/Triggers of MS. Speakers were David Hafler, Alberto Aschiero, Lisa Barcellos and Larry Steinman. And the top 6 are Genetics Tobacco smoking Vitamin D deficiency EBV infection Overweight in… Read More MS risk factors: the top 6
If you missed my blog on Klotho, you should check it out first before continuing. Below are the other four new things I learnt on the first full day of the American Neurological Association meeting, Chicago 2015: BIN1 is the second commonest monogenic genetic cause of Alzheimer’s disease (AD). And I never even heard of BIN1… Read More ANA 2015-Five new things
It’s the American Neurological Association‘s 140th Annual meeting in Chicago this weekend and my first attendance. It is holding at the grand Marriott Hotel on The Magnificent Mile. It is a rigorously academic meeting and the highlight for me on the first day is the presentation by the Gross Awardee, Dena Dubal, on the longevity… Read More Klotho, the elixir of life
Quite a few neurological disorders remain mysteries even when we know so much about them. Parkinson’s diseases (PD) is one of them. Dopamine deficiency is the established final common pathway, but why this deficiency presents in different ways is unclear. PD variants such as multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and Lewy body disease… Read More Parkinson’s disease-a few curious things
Gluten neurology is a controversial issue, to say the least! The heated debates between Sheffield and Nottingham may lie in the fog of history, but the issue simmers just below the surface. Gluten sensitivity, or coeliac disease, is a big time player in other body systems, but its neurological manifestations are clouded in mystery. A lot of… Read More Gluten neurology-persistent and growing?